Posh travel to the Weston Homes Community Stadium to face Colchester United.
Peterborough United make the trip to the Weston Homes Community Stadium in Sky Bet League One action on Saturday afternoon with struggling Colchester United the opposition (3pm).
The U's may still be in relegation trouble, but have shown signs of life in recent weeks with three wins and one draw in their last four league fixtures.
Graham Westley's men go into the game in 14th place after last weekend's 2-1 defeat to Rochdale at the ABAX Stadium.
The Posh boss is without the services of Jermaine Anderson, Joe Gormley and Jordan Nicholson due to injury, but all three are making good progress. Striker Tom Nichols will miss the rest of the season with a knee ligament injury.
Westley said: "We will face a team struggling at the bottom of the table and we know if we play to our level we can beat and beat well but if we are not on the money then we will struggle.”
Following Saturday's trip to the Weston Homes Community Stadium, Posh have a trip to Barnsley to look forward to on Tuesday evening.
"We want to end the season well, we know that our performances and results have not been good enough. The supporters have been magnificent both home and away this season, they have travelled to games in number and been very vocal with their backing," Westley added.
Posh have sold over 430 tickets in advance for the game with tickets available on the day at the stadium.
Tickets can be purchased in advance at www.theposhtickets.com, via the Ticketmaster hotline 0844 847 1934* and in person at the ABAX Stadium Box Office.
*calls cost 7ppm plus your network access charge.